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In the appropriate quantities, at the appropriate regularity, mucus is usually a lung’s ally. But if there’s too much of it, or if it’s way too sticky, it may betray the organ it had been meant to provide.
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The workforce centered on blocking a protein identified as synaptotagmin-2, or Syt2. Syt2 is found around the surface of the granules containing mucin. Fusion of those granules with the mobile membrane relies on Syt2 interacting with proteins within the mobile membrane.
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Lengthy chains of sugar molecules sprout from mucin’s area, predisposing the protein to absorb drinking water.
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The invention, described inside of a research posted March 23 in Character, could improve the lives of hundreds of thousands who experience airway obstruction resulting from free credits singapore excessive mucus.